What type of cancer are persons of Ashkenazi Jewish background at increased risk for?

Individuals of Ashkenazi Jewish descent are at an elevated risk for breast cancer primarily due to specific inherited genetic mutations, particularly in the BRCA1 and BRCA2 genes. These genetic mutations significantly increase the likelihood of developing breast and ovarian cancers. Research indicates that Ashkenazi Jews have a higher frequency of these mutations compared to other populations, contributing to their increased risk for breast cancer. This genetic predisposition emphasizes the importance of targeted screening and preventive measures for these individuals, highlighting the intersection of genetics and cancer susceptibility.