What is a common reaction of the body during the nadir phase following chemotherapy?

During the nadir phase following chemotherapy, the body typically experiences low blood cell counts, particularly affecting white blood cells. This reduction in white blood cells, known as leukopenia, significantly compromises the immune system, leaving the individual more susceptible to infections. The nadir phase is particularly critical as it is the time following chemotherapy when blood cell production is at its lowest, usually occurring about one to two weeks after treatment. This increased risk of infection is a key concern for healthcare providers, as patients may not have the immune capacity to fend off pathogens effectively.

In contrast, increased appetite and energy, high blood pressure and anxiety, or improved immune function are not typical responses during the nadir phase. Patients often experience fatigue, lack of appetite, and weakened immune responses during this time, illustrating the importance of monitoring and managing these risks in oncology nursing.