What is a classic symptom of disseminated intravascular coagulation (DIC)?

A classic symptom of disseminated intravascular coagulation (DIC) is mottled extremities. DIC is a serious condition characterized by widespread activation of the clotting cascade, leading to the formation of small blood clots throughout the blood vessels. This process can result in inadequate blood flow and oxygenation to various tissues, often leading to skin changes such as mottling. Mottled extremities are indicative of compromised perfusion, which can occur in conditions where DIC is present, such as severe infections, trauma, or obstetric complications.

In contrast, other symptoms listed, such as bradycardia, flank pain, and severe headache, are not classic manifestations of DIC. Bradycardia refers to a slow heart rate which may occur during various conditions but is not a hallmark of DIC. Flank pain may suggest renal issues or other abdominal pathologies, and while a severe headache can be associated with numerous conditions, it is not specifically linked to DIC. Therefore, mottled extremities are the most recognized symptom associated with this disorder, reflecting the underlying pathophysiological changes occurring in the body during DIC.